$149first month · then $279/mo
GLP-1 · Injection
GLP-1 injection
One simple injection per week. Semaglutide or tirzepatide protocol matched to your goals.
Weight loss, prescribed by a clinician you can talk to.
FDA-approved medication. A doctor who answers your messages within 24 hours. Results you can feel.
Pounds of fat off, every week. Real GLP-1, prescribed for your body.
Message your clinician directly. A US-licensed doctor replies within 24 hours.
$149first month
Licensed in all 50 statesHSA / FSA eligible
Clinical leadership
Dr. Jason Brill, MDChief Medical Officer
- 12+yrs in weight-loss medicine
- US-licensed clinicians
- MD-led care
Trusted by experts, priced for you.
Find the right GLP-1 medication with the confidence of knowing it's clinician-approved. Compounded and branded options, prescribed by US-licensed clinicians.
$99/mo membership + med cost
Brand · Wegovy®
Wegovy®
Branded semaglutide injection. We'll quote your total monthly cost upfront, based on insurance and supply.
$99/mo membership + med cost
Brand · Zepbound®
Zepbound®
Branded tirzepatide injection. We'll quote your total monthly cost upfront, based on insurance and supply.
The shift
The change we've all been waiting for.
This is what science makes possible. Care that finally fits a life.
- 6×More weight lost than diet and exercise alone
- 18%Average reduction in body weight
- 86%Achieved meaningful weight loss
* Trial averages from STEP-1 (semaglutide, NEJM 2021) and SURMOUNT-1 (tirzepatide, NEJM 2022). Individual results vary.
Your numbers
Want to reach your goal weight fast?
It's not magic. It's science. GLP-1 is a naturally occurring hormone that regulates appetite and blood sugar, improves your metabolism, and knocks out cravings.
Get startedYour current weight200lbs
Potential weight loss*42lbs
* Estimate based on SURMOUNT-1 trial average (tirzepatide, 72 weeks, NEJM 2022). Not a guarantee. Individual results vary.
Why it works
Backed by clinical trials. It works.
In clinical trials, GLP-1 medications help patients lose 15–20% of their body weight on average.
- 21%Average body weight lost in trials
- 63%Patients lost 20%+ of their body weight
- 20%Lower risk of heart attack or stroke
- 35%Fewer calories eaten, without willpower
* From clinical trials: SURMOUNT-1 (tirzepatide, NEJM 2022), SELECT (semaglutide, NEJM 2023, patients with established cardiovascular disease), and Friedrichsen et al. (semaglutide, Diabetes Obes Metab 2021). Individual results vary.
From visit to door, about a week.
No phone trees, no waiting rooms. The whole intake takes three minutes; everything that matters is done by a person.
Average time from completed assessment to medication shipped: 6 days.
01Step one · 3 minutes
Take the assessment.
A short, plainspoken intake. Labs, history, the medicines you've tried.
Average completion time: 3 minutes 12 seconds.
02Step two · Within 24 hours
A clinician reads it.
A US-licensed clinician reviews everything you wrote, asks follow-ups if needed, and writes a plan.
Built to the clinical standards of our Chief Medical Officer.
03Step three · About a week
Medicine arrives.
Compounded in a US 503A pharmacy and shipped to your door, in a plain box, every month.
Free, expedited shipping nationwide. Cancel anytime.
Always-on care
Unlimited support, around the clock.
Mainstay clinicians handle appointments and follow-ups. Instant answers from your care assistant, any time, day or night. Reach out for guidance, ask a question, or raise a concern.
Begin a visit
MainstayCare assistant
MainstayCare assistant
Frequently asked questions
How much does the program cost?
Mainstay offers two paths. Compounded GLP-1 is $149 your first month and $279 for refills, all-in: medication included, no pharmacy stop, no insurance needed. Compounded pricing stays the same at every dose. For branded options like Wegovy or Zepbound, clinical care is $99/mo and the medication is filled at your pharmacy (where your insurance may cover some or all of it). We quote your full monthly total upfront so there are no surprises.What medication will I be prescribed?
Mainstay clinicians prescribe both compounded GLP-1 (most commonly semaglutide and tirzepatide) and branded medications like Wegovy and Zepbound. Your clinician will recommend what fits your goals, health history, and budget. Compounded medications ship from US-based 503A and 503B compounding pharmacies, with every batch tested for potency, sterility, and identity. Branded prescriptions are written by your clinician and filled at your pharmacy.Am I eligible for Mainstay?
Most adults with a BMI of 27 or higher (or 30 without related conditions) are candidates for GLP-1 treatment. Your clinician will review your full medical history, current medications, and goals before recommending a plan. Mainstay currently serves most US states. If you're not eligible after the clinician review, you won't be charged and no medication ships.What are the side effects?
The most common side effects of GLP-1 medications are nausea, constipation, diarrhea, fatigue, and reflux. These usually appear in the first few weeks and ease as your body adjusts to the dose. Rare but serious risks include pancreatitis and gallbladder issues; your clinician will screen for these before prescribing. You can reach out anytime in your Mainstay portal if anything feels off.What if my insurance doesn't cover it?
Mainstay doesn't bill insurance directly, since that lets us keep pricing transparent and skip the months of claim-chasing that drive costs up elsewhere. For compounded GLP-1, insurance isn't needed: your $149 or $279 covers everything. For branded medications like Wegovy or Zepbound, you'll fill the prescription at your pharmacy and can use your insurance there. We quote your expected total upfront so you know what you're committing to before treatment starts.What happens after I sign up?
You'll complete a three-minute intake covering your goals, weight, medical history, and current medications. A US-licensed clinician reviews your answers within 24 hours and either approves treatment or follows up with questions. Once approved, your medication ships from the pharmacy to your door, usually within 3-5 days.Can I pause or cancel?
Yes, anytime, from your Mainstay portal. There's no contract and no commitment. If you want to pause for a month, do it. If you want to stop entirely, do it. Your clinician is also available to help you taper safely if you decide to come off treatment, so there are no awkward conversations and no fees.
When you're ready
Care that stays. One visit away.
A three-minute assessment, reviewed by a US clinician within 24 hours.
GLP-1 weight loss program$149 first monthThen $279/mo. Includes medication, labs, shipping, and unlimited clinician follow-ups. Cancel anytime.
3-minute intakeReply within 24 hoursCancel anytimeLicensed in all 50 states
- HSA / FSA eligibleUse your benefits card
- Licensed in all 50 statesWherever you live
- Free, expedited shippingCold-chain, 2-day
- Cancel anytimeOnline, in two clicks